Which checkpoint in the cell cycle checks the integrity of DNA after replication?

The G2 checkpoint is crucial for checking the integrity of DNA after replication, ensuring that any errors or damage that may have occurred during the S phase are identified and addressed before the cell proceeds to mitosis. This checkpoint serves as a quality control mechanism, allowing the cell to confirm that its DNA is intact and accurately replicated. If any issues are detected, the cell can either attempt to repair the damaged DNA or, if the damage is irreparable, initiate programmed cell death (apoptosis) to prevent the propagation of faulty genetic material. This regulatory process helps maintain genomic stability and prevents the development of diseases, such as cancer, that can result from mutations.